https://www.peptomiq.com/lab-notes Peptide vendor purity audits, study summaries and analytical methods from the Peptomiq science team. en-us Fri, 01 May 2026 15:19:32 GMT https://www.peptomiq.com/lab-notes/tb-500-vendor-purity-audit-2026 https://www.peptomiq.com/lab-notes/tb-500-vendor-purity-audit-2026 We assayed TB-500 from 10 research-peptide vendors by RP-HPLC and LC-MS. Six passed >97% purity, two were truncated fragments, one was thymosin beta-4 1-44 only. Wed, 22 Apr 2026 00:00:00 GMT TB-500 thymosin beta-4 vendor purity HPLC LC-MS quality control Vendor Tests https://www.peptomiq.com/lab-notes/how-we-test-peptide-purity-hplc-ms-2026 https://www.peptomiq.com/lab-notes/how-we-test-peptide-purity-hplc-ms-2026 A transparent walk-through of the column, gradient, detector and mass-spec settings we use to verify research-peptide purity to 0.1% — and what numbers on a COA actually mean. Tue, 28 Apr 2026 00:00:00 GMT HPLC LC-MS purity testing methodology certificate of analysis quality control Methods https://www.peptomiq.com/lab-notes/semaglutide-vs-tirzepatide-receptor-pharmacology-2026 https://www.peptomiq.com/lab-notes/semaglutide-vs-tirzepatide-receptor-pharmacology-2026 GLP-1 mono-agonism vs dual GLP-1/GIP agonism — receptor binding affinities, downstream signaling differences, and what the head-to-head SURMOUNT-5 data does and doesn't tell us. Sat, 18 Apr 2026 00:00:00 GMT semaglutide tirzepatide GLP-1 GIP incretin receptor pharmacology Study Summary https://www.peptomiq.com/lab-notes/endotoxin-testing-lal-vs-rfc-2026 https://www.peptomiq.com/lab-notes/endotoxin-testing-lal-vs-rfc-2026 How we screen every Peptomiq lot for endotoxin contamination — the LAL kinetic-chromogenic assay, why we cross-check with recombinant Factor C, and the EU/USP limits we hold to. Wed, 15 Apr 2026 00:00:00 GMT endotoxin LAL rFC quality control USP methods Methods https://www.peptomiq.com/lab-notes/ipamorelin-vs-cjc-1295-stack-pharmacology-2026 https://www.peptomiq.com/lab-notes/ipamorelin-vs-cjc-1295-stack-pharmacology-2026 Ipamorelin is a ghrelin-mimetic; CJC-1295 with DAC is a long-acting GHRH analog. We walk through the two-receptor synergy, half-life mismatch, and what the rodent pulse-amplitude data shows. Fri, 10 Apr 2026 00:00:00 GMT ipamorelin CJC-1295 GHRH ghrelin growth hormone stack Study Summary https://www.peptomiq.com/lab-notes/bpc-157-tendon-healing-study-summary-2026 https://www.peptomiq.com/lab-notes/bpc-157-tendon-healing-study-summary-2026 Plain-English summary of a 2024 rat Achilles-transection study showing accelerated collagen organization with BPC-157 — endpoints, dosing schedule, controls and what the data does and doesn't show. Tue, 28 Apr 2026 00:00:00 GMT BPC-157 tendon repair tissue repair rat model study summary collagen Study Summary https://www.peptomiq.com/lab-notes/epitalon-telomere-research-summary-2026 https://www.peptomiq.com/lab-notes/epitalon-telomere-research-summary-2026 A critical summary of the Khavinson telomere literature on Epitalon — what telomerase activation has been measured in vitro, the 12-year human cohort claims, and the replication gaps. Sat, 04 Apr 2026 00:00:00 GMT epitalon telomerase longevity Khavinson study summary Study Summary https://www.peptomiq.com/lab-notes/peptide-reconstitution-bacteriostatic-water-stability-2026 https://www.peptomiq.com/lab-notes/peptide-reconstitution-bacteriostatic-water-stability-2026 We ran a 60-day stability study on six common research peptides reconstituted in 0.9% benzyl-alcohol bacteriostatic water. Degradation curves, refrigeration impact, and which peptides die first. Sat, 28 Mar 2026 00:00:00 GMT reconstitution stability bacteriostatic water BPC-157 ipamorelin methods Methods https://www.peptomiq.com/lab-notes/mots-c-mitochondrial-research-summary-2026 https://www.peptomiq.com/lab-notes/mots-c-mitochondrial-research-summary-2026 MOTS-c is a 16-aa mitochondrial-derived peptide that activates AMPK. We summarize the rodent metabolic data, the human exercise-cohort observations, and what the AMPK pathway means in practice. Sun, 22 Mar 2026 00:00:00 GMT MOTS-c mitochondrial AMPK metabolic health longevity Study Summary https://www.peptomiq.com/lab-notes/selank-vs-semax-cognitive-research-comparison-2026 https://www.peptomiq.com/lab-notes/selank-vs-semax-cognitive-research-comparison-2026 Selank is an anxiolytic tuftsin analog; Semax is an ACTH 4-10 fragment with BDNF-upregulating effects. Side-by-side mechanism, intranasal pharmacokinetics, and the rodent behavioral data. Sun, 15 Mar 2026 00:00:00 GMT selank semax nootropic BDNF anxiolytic intranasal Study Summary https://www.peptomiq.com/lab-notes/bpc-157-vendor-purity-audit-2026 https://www.peptomiq.com/lab-notes/bpc-157-vendor-purity-audit-2026 We assayed BPC-157 from 12 research-peptide vendors by reverse-phase HPLC. Eight passed >97%, three failed below 90%, one was undetectable. Full results inside. Wed, 15 Apr 2026 00:00:00 GMT BPC-157 vendor purity HPLC research peptides quality control Vendor Tests https://www.peptomiq.com/lab-notes/ghk-cu-skin-research-summary-2026 https://www.peptomiq.com/lab-notes/ghk-cu-skin-research-summary-2026 GHK-Cu is a copper-binding tripeptide implicated in collagen, elastin and decorin synthesis. We summarize the in-vitro fibroblast data, the topical wound-healing trials, and the copper-toxicity ceiling. Sun, 08 Mar 2026 00:00:00 GMT GHK-Cu copper peptide collagen wound healing skin research Study Summary https://www.peptomiq.com/lab-notes/glp1-class-comparison-2026 https://www.peptomiq.com/lab-notes/glp1-class-comparison-2026 A research-context summary of the GLP-1, GIP and glucagon receptor activity profiles for semaglutide, tirzepatide and retatrutide. With half-lives, study endpoints and citation pointers. Wed, 15 Apr 2026 00:00:00 GMT semaglutide tirzepatide retatrutide GLP-1 GIP incretin research Study Summary